Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | HTR2C | P28335 | 1/20 | 0.67 |
| ▸ | HTR2B | P41595 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305776 | 0.94 | — | — | |
| SCHEMBL7297864 | 0.89 | — | — | |
| SCHEMBL7296095 | 0.89 | — | — | |
| SCHEMBL7296727 | 0.87 | — | — | |
| SCHEMBL7305578 | 0.85 | BCHE (0.53) | — | |
| SCHEMBL466899 | 0.82 | SIGMAR1 (0.68) | SIGMAR1 | |
| SCHEMBL7304639 | 0.82 | SLC6A4 (0.60) | HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL7299780 | 0.81 | CARM1 (0.60) | SIGMAR1 | |
| SCHEMBL9341776 | 0.80 | KDM4E (0.59) | — | |
| SCHEMBL9339796 | 0.80 | HTR2A (0.57) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449187-A2 | Piperidin ether derivatives as psychotropic drugs or plant fungicides | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-10-02 | — | — | EP | disclosed |