Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340596 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL9341744 | 0.93 | — | — | |
| SCHEMBL7310558 | 0.80 | DRD2 (0.67) | HTR2AHTR2C | |
| SCHEMBL10587379 | 0.79 | ALDH1A1 (0.57) | HTR2AHTR2CKCNH2 | |
| SCHEMBL7296727 | 0.78 | — | — | |
| SCHEMBL29208105 | 0.78 | HTR2A (0.52) | HTR2AHTR2CKCNH2 | |
| SCHEMBL9343644 | 0.77 | HTR2A (0.59) | HTR2AHTR2CKCNH2 | |
| SCHEMBL9341776 | 0.77 | KDM4E (0.59) | — | |
| SCHEMBL9339578 | 0.76 | MEN1 (0.51) | HTR2AHTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL9340630 | 0.76 | HTR2A (0.58) | HTR2AHTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317997-B1 | 1,4-Disubstituted-piperidinyl compounds | MERRELL DOW PHARMA (US) | 1994-06-15 | — | — | EP | claimed |
| US-4870083-A | 1,4-Disubstituted-piperidinyl compounds useful as analgesics and muscle relaxants | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-09-26 | — | — | US | claimed |
| CN-1034202-A | 1, the 4-Disubstituted-piperidnyl compounds | MERRELL DOW PHARMA (US) | 1989-07-26 | — | — | CN | claimed |
| EP-0317997-A2 | 1,4-Disubstituted-piperidinyl compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-05-31 | — | — | EP | claimed |
| EP-0317997-B1 | 1,4-Disubstituted-piperidinyl compounds | MERRELL DOW PHARMA (US) | 1994-06-15 | — | — | EP | disclosed |
| US-4870083-A | 1,4-Disubstituted-piperidinyl compounds useful as analgesics and muscle relaxants | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-09-26 | — | — | US | disclosed |
| CN-1034202-A | 1, the 4-Disubstituted-piperidnyl compounds | MERRELL DOW PHARMA (US) | 1989-07-26 | — | — | CN | disclosed |
| EP-0317997-A2 | 1,4-Disubstituted-piperidinyl compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-05-31 | — | — | EP | disclosed |