Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752959 | 1.00 | EBP (0.51) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL5756895 | 0.86 | EBP (0.39) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL7310837 | 0.86 | EBP (0.52) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL5754384 | 0.85 | EBP (0.38) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL5755590 | 0.85 | EBP (0.38) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL7314781 | 0.85 | EBP (0.38) | EBPSIGMAR1CYP3A4CYP2D6DRD2 | |
| SCHEMBL5243028 | 0.84 | EBP (0.47) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL7305092 | 0.84 | EBP (0.47) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL7308677 | 0.84 | ABCB1 (0.40) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL5751378 | 0.83 | EBP (0.38) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |