Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243028 | 1.00 | EBP (0.47) | EBPSIGMAR1CYP2D6CYP3A4L3MBTL1 | |
| SCHEMBL5755328 | 0.85 | EBP (0.48) | EBPSIGMAR1CYP2D6CYP3A4L3MBTL1 | |
| SCHEMBL7310593 | 0.84 | EBP (0.51) | EBPSIGMAR1CYP2D6CYP3A4L3MBTL1 | |
| SCHEMBL5752959 | 0.84 | EBP (0.51) | EBPSIGMAR1CYP2D6CYP3A4L3MBTL1 | |
| SCHEMBL7310100 | 0.78 | EBP (0.43) | EBPSIGMAR1CYP2D6CYP3A4L3MBTL1 | |
| SCHEMBL7310097 | 0.78 | EBP (0.43) | EBPSIGMAR1CYP2D6CYP3A4L3MBTL1 | |
| SCHEMBL7314647 | 0.77 | EBP (0.42) | EBPSIGMAR1CYP2D6CYP3A4L3MBTL1 | |
| SCHEMBL7314643 | 0.77 | EBP (0.42) | EBPSIGMAR1CYP2D6CYP3A4L3MBTL1 | |
| SCHEMBL7314638 | 0.77 | EBP (0.42) | EBPSIGMAR1CYP2D6CYP3A4L3MBTL1 | |
| SCHEMBL7753625 | 0.76 | EBP (0.56) | EBPSIGMAR1CYP2D6CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |