Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.63 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.57 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694822 | 0.92 | AGTR1 (0.57) | AGTR1AGTR2GP6 | |
| SCHEMBL9429755 | 0.91 | AGTR1 (0.57) | AGTR1AGTR2GP6 | |
| SCHEMBL9309106 | 0.90 | AGTR1 (0.77) | AGTR1AGTR2 | |
| SCHEMBL9310972 | 0.88 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL9309628 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2GP6 | |
| SCHEMBL7299689 | 0.86 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL9695755 | 0.85 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9309479 | 0.84 | AGTR1 (0.48) | AGTR1 | |
| SCHEMBL9308896 | 0.84 | AGTR1 (0.60) | AGTR1AGTR2GP6 | |
| SCHEMBL9310803 | 0.83 | AGTR1 (0.72) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514193-A1 | N-linked imidazolyl-methyl benzofuran derivatives with antihypotensive activity | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |