Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309977 | 0.94 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL9309646 | 0.93 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL9309997 | 0.93 | AGTR1 (0.64) | AGTR1 | |
| SCHEMBL9309106 | 0.92 | AGTR1 (0.77) | AGTR1AGTR2 | |
| SCHEMBL7299700 | 0.90 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9309664 | 0.90 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9695832 | 0.90 | AGTR1 (0.62) | AGTR1 | |
| SCHEMBL9310803 | 0.89 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL7301212 | 0.88 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL9695755 | 0.88 | AGTR1 (0.66) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310927-A | Hypotensive agents; cognition activators; imidazolyl-2-aryl derivatives | GLAXO GROUP LIMITED (GB) | 1994-05-10 | — | — | US | disclosed |
| EP-0514193-A1 | N-linked imidazolyl-methyl benzofuran derivatives with antihypotensive activity | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |