Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 19/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 19/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312688 | 0.89 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL7316240 | 0.84 | PDE3B (0.71) | PDE3BPDE3A | |
| SCHEMBL7306886 | 0.84 | PDE3B (0.48) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL7318826 | 0.81 | PDE3B (0.58) | PDE3BPDE3A | |
| SCHEMBL7318331 | 0.80 | PDE3B (0.48) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL7318939 | 0.79 | PDE3B (0.50) | PDE3BPDE3A | |
| SCHEMBL7316912 | 0.79 | PDE3B (0.63) | PDE3BPDE3A | |
| SCHEMBL7310848 | 0.78 | PDE3B (0.52) | PDE3BPDE3A | |
| SCHEMBL7307748 | 0.78 | PDE3B (0.48) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL7313823 | 0.76 | PDE3B (0.53) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |