Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 8/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310848 | 0.83 | PDE3B (0.52) | PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL7311992 | 0.81 | PDE3B (0.58) | PDE3BPDE3A | |
| SCHEMBL7317443 | 0.76 | RAB9A (0.45) | PDE3BPDE3ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7318826 | 0.76 | PDE3B (0.58) | PDE3BPDE3A | |
| SCHEMBL7317227 | 0.73 | PDE3B (0.60) | PDE3BPDE3A | |
| SCHEMBL7316240 | 0.72 | PDE3B (0.71) | PDE3BPDE3A | |
| SCHEMBL7312634 | 0.71 | PDE3B (0.44) | PDE3BPDE3ARAB9ANPC1MEN1 | |
| SCHEMBL7309559 | 0.71 | PDE3B (0.52) | PDE3BPDE3A | |
| SCHEMBL7313823 | 0.70 | PDE3B (0.53) | PDE3BPDE3A | |
| SCHEMBL7318939 | 0.69 | PDE3B (0.50) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |