SCHEMBL10691220

SCHEMBL10691220

NS(=O)(=O)c1ccccc1CCCl

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 11/20 0.47
CA1 P00915 9/20 0.47
CA9 Q16790 7/20 0.47
CA6 P23280 4/20 0.47
CA12 O43570 4/20 0.47
CA7 P43166 4/20 0.47
CA5A P35218 4/20 0.47
CA4 P22748 3/20 0.47
CA5B Q9Y2D0 3/20 0.47
CA14 Q9ULX7 2/20 0.47
CYP2C9 P11712 1/20 0.47
PTGES2 Q9H7Z7 5/20 0.45
LDHA P00338 1/20 0.37
CDK2 P24941 1/20 0.37
CA3 P07451 1/20 0.37
PLA2G7 Q13093 1/20 0.37
CA13 Q8N1Q1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8349565 0.87 CA2 (0.54) CA2CA1CA9CA6CA12
SCHEMBL30395701 0.83 CA2 (0.50) CA2CA1CA9CA6CA12
SCHEMBL587388 0.83 GAA (0.41) PTGES2
SCHEMBL10572285 0.83 CA2 (0.50) CA2CA1CA9CA6CA12
SCHEMBL27810678 0.83 PTGES2 (0.42) CA2CA1CA9CA6CA12
SCHEMBL27831133 0.82 PTGES2 (0.40) CA2CA1CA9CA6CA12
SCHEMBL11254980 0.82 ALDH1A1 (0.38) CA2CA1CA9CA6CA12
SCHEMBL731097 0.82 TAAR1 (0.52) CA2CA1CA9CA6CA12
SCHEMBL8355995 0.82 CA2 (0.48) CA2CA1CA9CA6CA12
SCHEMBL1807854 0.82 CA2 (0.48) CA2CA1CA9CA6CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4770690-A Herbicidal ortho-alkyl- and ortho-alkenyl-substituted benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-13 US disclosed
EP-0106512-B1 HERBICIDAL ORTHO-ALKYL- AND ORTHO-ALKENYL-SUBSTITUTED BENZENESULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-18 EP disclosed
US-4699650-A Herbicidal ortho-alkyl-and ortho-alkenyl substituted benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-10-13 US disclosed
US-4678502-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-07-07 US disclosed
EP-0106512-A2 Herbicidal ortho-alkyl- and ortho-alkenyl-substituted benzenesulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-04-25 EP disclosed
US-3956385-A REACTING SULFONYLHALIDE WITH 2-CHLORO-ETHYLAMINE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-11 US disclosed