Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299996 | 0.95 | SORD (0.60) | SORDGAAKMT2AALDH1A1KCNH2 | |
| SCHEMBL15941341 | 0.87 | SORD (0.57) | SORDGAAKMT2AALDH1A1KCNH2 | |
| SCHEMBL2624458 | 0.85 | SORD (0.58) | SORDGAAKMT2AKCNH2LMNA | |
| SCHEMBL30903262 | 0.83 | ELANE (0.57) | SORDGAAKMT2AKCNH2LMNA | |
| SCHEMBL5021493 | 0.80 | ELANE (0.61) | SORDGAAKMT2AALDH1A1KCNH2 | |
| SCHEMBL31472604 | 0.80 | ELANE (0.61) | SORDGAAKMT2AALDH1A1KCNH2 | |
| SCHEMBL5021499 | 0.80 | GAA (0.53) | SORDGAAKMT2AKCNH2LMNA | |
| SCHEMBL7534443 | 0.79 | DRD3 (0.55) | SORDGAAKMT2AALDH1A1KCNH2 | |
| SCHEMBL13091233 | 0.79 | DRD3 (0.55) | SORDGAAKMT2AKCNH2DRD3 | |
| SCHEMBL5021503 | 0.79 | ELANE (0.62) | SORDGAAKMT2AALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621271-B1 | Benzoxazole derivatives and their use as serotonin 5-HT3 receptor antagonists | MEIJI SEIKA KAISHA (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5631257-A | ANTISEROTONIN AGENTS FOR TREATMENT OF NAUSEA AND ANTIEMETICS | MEIJI SEIKA KAISHA, LTD. (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0621271-A1 | Benzoxazole derivatives and their use as serotonin 5-HT3 receptor antagonists | MEIJI SEIKA KAISHA LTD. (JP) | 1994-10-26 | — | — | EP | disclosed |