Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SORD | Q00796 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2056153 | 0.94 | GAA (0.58) | GAAKMT2ASORDLMNASMN1; SMN2 | |
| SCHEMBL2624458 | 0.91 | SORD (0.58) | GAAKMT2ASORDLMNASMN1; SMN2 | |
| SCHEMBL30903262 | 0.89 | ELANE (0.57) | GAAKMT2ASORDLMNASMN1; SMN2 | |
| SCHEMBL5021493 | 0.86 | ELANE (0.61) | GAAKMT2ASORDLMNASMN1; SMN2 | |
| SCHEMBL31472604 | 0.86 | ELANE (0.61) | GAAKMT2ASORDLMNASMN1; SMN2 | |
| SCHEMBL1981175 | 0.84 | ELANE (0.62) | GAAKMT2ASORDLMNASMN1; SMN2 | |
| SCHEMBL5021503 | 0.84 | ELANE (0.62) | GAAKMT2ASORDLMNASMN1; SMN2 | |
| SCHEMBL6488417 | 0.83 | FAAH (0.51) | — | |
| SCHEMBL6488071 | 0.81 | PTGES (0.57) | — | |
| SCHEMBL7311154 | 0.80 | SORD (0.55) | GAAKMT2ASORDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178666-B2 | 2-aminobenzoxazole process | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| EP-0621271-B1 | Benzoxazole derivatives and their use as serotonin 5-HT3 receptor antagonists | MEIJI SEIKA KAISHA (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5631257-A | ANTISEROTONIN AGENTS FOR TREATMENT OF NAUSEA AND ANTIEMETICS | MEIJI SEIKA KAISHA, LTD. (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0621271-A1 | Benzoxazole derivatives and their use as serotonin 5-HT3 receptor antagonists | MEIJI SEIKA KAISHA LTD. (JP) | 1994-10-26 | — | — | EP | disclosed |