SCHEMBL7311176

SCHEMBL7311176

O=C(O)C1CC1c1ccc(C2CCCCC2)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.42
FFAR1 O14842 4/20 0.41
CYP4F2 P78329 2/20 0.39
CYP4A11 Q02928 2/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
ACMSD Q8TDX5 1/20 0.38
S1PR4 O95977 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
S1PR5 Q9H228 1/20 0.38
SLC9A1 P19634 1/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 1/20 0.38
APP P05067 1/20 0.38
KDM1A O60341 1/20 0.37
MAOA P21397 1/20 0.37
OPRL1 P41146 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7346188 0.99 KMO (0.41) KMOFFAR1CYP4F2CYP4A11PTGDR2
SCHEMBL7346168 0.89 OPRL1 (0.38) KMOPTGDR2ACMSDS1PR4S1PR1
SCHEMBL7312887 0.83 FFAR1 (0.44) KMOFFAR1PTGDR2ACMSDSLC9A1
Hydrochloric Acid SCHEMBL7315858 0.82 FFAR1 (0.43) KMOFFAR1PTGDR2ACMSDHPGD
SCHEMBL7309756 0.79 SLC18A3 (0.42) KMOFFAR1ACMSDSLC9A1HTT
SCHEMBL7655989 0.79 FFAR1 (0.50) FFAR1CYP4F2CYP4A11SLC9A1KDM1A
SCHEMBL248384 0.79 FFAR1 (0.50) FFAR1CYP4F2CYP4A11SLC9A1KDM1A
SCHEMBL12915852 0.79 FFAR1 (0.50) FFAR1CYP4F2CYP4A11SLC9A1KDM1A
SCHEMBL248385 0.79 FFAR1 (0.50) FFAR1CYP4F2CYP4A11SLC9A1KDM1A
SCHEMBL18272446 0.79 FFAR1 (0.50) FFAR1CYP4F2CYP4A11SLC9A1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235791-B1 USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE SANOFI-SYNTHELABO (FR) 2001-05-22 US disclosed