SCHEMBL7312887

SCHEMBL7312887

O=C(O)C1CC1c1ccc(C2CCCCC2)c(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.44
KMO O15229 1/20 0.42
STING1 Q86WV6 1/20 0.41
FFAR2 O15552 1/20 0.40
PTGDR2 Q9Y5Y4 5/20 0.39
PTGDR Q13258 3/20 0.39
PTGER2 P43116 1/20 0.39
ACMSD Q8TDX5 1/20 0.38
IDO1 P14902 1/20 0.38
CEL P19835 1/20 0.37
NSD2 O96028 1/20 0.37
NSD1 Q96L73 1/20 0.37
NSD3 Q9BZ95 1/20 0.37
LPAR5 Q9H1C0 1/20 0.37
HPSE Q9Y251 1/20 0.37
HPGD P15428 1/20 0.37
SLC9A1 P19634 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7315858 0.99 FFAR1 (0.43) FFAR1KMOSTING1FFAR2PTGDR2
SCHEMBL7315840 0.90 CEL (0.38) KMOSTING1FFAR2PTGDR2PTGDR
SCHEMBL7311176 0.83 KMO (0.42) FFAR1KMOPTGDR2ACMSDHPGD
SCHEMBL7322549 0.83 SIGMAR1 (0.48)
Hydrochloric Acid SCHEMBL7346188 0.82 KMO (0.41) FFAR1KMOPTGDR2ACMSDHPGD
SCHEMBL7320685 0.81 SIGMAR1 (0.42) PTGDR2PTGDRPTGER2
SCHEMBL7313183 0.81 FFAR1 (0.41) FFAR1KMOACMSDIDO1HPGD
SCHEMBL7323050 0.80 HRH3 (0.53)
Hydrochloric Acid SCHEMBL7319313 0.80 FFAR1 (0.40) FFAR1KMOACMSDIDO1HPGD
SCHEMBL7319063 0.80 HRH3 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235791-B1 USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE SANOFI-SYNTHELABO (FR) 2001-05-22 US disclosed