Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.41 |
| ▸ | ACE | P12821 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311444 | 1.00 | PKM (0.45) | PKMGAAITGB3ITGA2BACE | |
| SCHEMBL7366324 | 0.92 | PKM (0.44) | PKMGAAITGB3ITGA2BL3MBTL1 | |
| SCHEMBL7366326 | 0.92 | PKM (0.44) | PKMGAAITGB3ITGA2BL3MBTL1 | |
| SCHEMBL7296978 | 0.84 | PLA2G10 (0.43) | PKMGAAL3MBTL1BRD4KDM4E | |
| SCHEMBL7296969 | 0.84 | PLA2G10 (0.43) | PKMGAAL3MBTL1BRD4KDM4E | |
| Oxalic Acid SCHEMBL7298195 | 0.84 | PLA2G10 (0.41) | PKMGAAITGB3ITGA2BL3MBTL1 | |
| Oxalic Acid SCHEMBL7298168 | 0.84 | PLA2G10 (0.41) | PKMGAAITGB3ITGA2BL3MBTL1 | |
| SCHEMBL27381852 | 0.81 | PKM (0.45) | PKMGAAITGB3ITGA2BACE | |
| Hydrochloric Acid SCHEMBL7277753 | 0.80 | PKM (0.44) | PKMGAAITGB3ITGA2BACE | |
| Hydrochloric Acid SCHEMBL7277734 | 0.80 | PKM (0.44) | PKMGAAITGB3ITGA2BACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0643072-B1 | 2-Piperazinone compounds and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-02-24 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |
| US-5550131-A | ANTITHROMBOTIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0643072-A1 | 2-Piperazinone compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1995-03-15 | — | — | EP | disclosed |