Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 2/20 | 0.31 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.31 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296978 | 1.00 | PLA2G10 (0.43) | PLA2G10PLA2G5PKMGAABRD4 | |
| Oxalic Acid SCHEMBL7298195 | 0.96 | PLA2G10 (0.41) | PLA2G10PLA2G5PKMGAABRD4 | |
| Oxalic Acid SCHEMBL7298168 | 0.96 | PLA2G10 (0.41) | PLA2G10PLA2G5PKMGAABRD4 | |
| SCHEMBL7278907 | 0.94 | PLA2G10 (0.45) | PLA2G10PLA2G5PKMGAAPOLB | |
| Hydrochloric Acid SCHEMBL7278550 | 0.92 | PLA2G10 (0.44) | PLA2G10PLA2G5PKMGAAPOLB | |
| SCHEMBL7366324 | 0.90 | PKM (0.44) | PKMGAABRD4L3MBTL1KDM4E | |
| SCHEMBL7366326 | 0.90 | PKM (0.44) | PKMGAABRD4L3MBTL1KDM4E | |
| SCHEMBL7314096 | 0.88 | PLA2G10 (0.41) | PLA2G10PLA2G5PKMGAAPOLB | |
| SCHEMBL7311432 | 0.84 | PKM (0.45) | PKMGAABRD4L3MBTL1KDM4E | |
| SCHEMBL7311444 | 0.84 | PKM (0.45) | PKMGAABRD4L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6204268-B1 | CYCLIC DIAZA COMPOUNDS | COR THERAPEUTICS, INC | 2001-03-20 | — | — | US | disclosed |
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0643072-B1 | 2-Piperazinone compounds and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-02-24 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |
| US-5550131-A | ANTITHROMBOTIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0643072-A1 | 2-Piperazinone compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1995-03-15 | — | — | EP | disclosed |