Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311564 | 1.00 | FOLH1 (0.43) | FOLH1TPSAB1TPSD1TPSG1MAPT | |
| SCHEMBL7373560 | 0.89 | ELANE (0.37) | TPSAB1TPSD1TPSG1MMP2MMP9 | |
| SCHEMBL7373562 | 0.89 | ELANE (0.37) | TPSAB1TPSD1TPSG1MMP2MMP9 | |
| SCHEMBL7319787 | 0.83 | TGM2 (0.45) | ELANE | |
| SCHEMBL7371476 | 0.82 | FOLH1 (0.40) | FOLH1TPSAB1TPSD1TPSG1ELANE | |
| SCHEMBL7371479 | 0.82 | FOLH1 (0.40) | FOLH1TPSAB1TPSD1TPSG1ELANE | |
| SCHEMBL7313381 | 0.81 | TGM2 (0.46) | ELANE | |
| SCHEMBL7379636 | 0.79 | TPSAB1 (0.44) | FOLH1TPSAB1TPSD1TPSG1KMT2A | |
| SCHEMBL7379638 | 0.79 | TPSAB1 (0.44) | FOLH1TPSAB1TPSD1TPSG1KMT2A | |
| SCHEMBL7318925 | 0.78 | ELANE (0.37) | TPSAB1TPSD1TPSG1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110812-A | Treatment of pancreatitis; anticoagulants | BRISTOL-MYERS SQUIBB CO. (US) | 1992-05-05 | — | — | US | claimed |
| US-5326863-A | Antithrombin and antitrypsin activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-07-05 | — | — | US | disclosed |
| US-5175283-A | Enzyme inhibitors for antitrypsin or antithrombin as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| US-5110812-A | Treatment of pancreatitis; anticoagulants | BRISTOL-MYERS SQUIBB CO. (US) | 1992-05-05 | — | — | US | disclosed |
| US-5037819-A | Anticoagulant; treating pancreatitis | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-08-06 | — | — | US | disclosed |