Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309234 | 0.91 | PDE3B (0.35) | PDE3BPDE3AKCNQ2KCNA5TSHR | |
| SCHEMBL7312230 | 0.86 | KMT2A (0.39) | PDE3BPDE3ATSHRGAAMAPT | |
| SCHEMBL7321069 | 0.86 | PDE4A (0.43) | PDE3BPDE3AKCNA5TSHRGAA | |
| SCHEMBL7316957 | 0.85 | PDE3B (0.35) | NPC1PDE3BPDE3AKCNQ2TSHR | |
| SCHEMBL7318644 | 0.82 | PDE3B (0.35) | NPC1RAB9APDE3BPDE3AKCNQ2 | |
| SCHEMBL7320179 | 0.82 | PDE4A (0.38) | NPC1RAB9APDE3BPDE3APPIA | |
| SCHEMBL7308383 | 0.81 | PDE3B (0.41) | NPC1PDE3BPDE3AKCNQ2TSHR | |
| SCHEMBL7313145 | 0.80 | PDE4A (0.43) | NPC1PDE3BPDE3AKCNQ2TSHR | |
| SCHEMBL7311655 | 0.79 | PDE3B (0.38) | PDE3BPDE3AKCNA5TSHRGAA | |
| SCHEMBL7317651 | 0.77 | PDE3B (0.38) | NPC1RAB9APDE3BPDE3AKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |