Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17594318 | 0.82 | MPO (0.65) | LTA4HMPOSLC6A4CA2 | |
| SCHEMBL197022 | 0.81 | HDAC3 (0.57) | HDAC1 | |
| SCHEMBL27791780 | 0.80 | CYP2D6 (0.45) | — | |
| Hydrochloric Acid SCHEMBL7434059 | 0.80 | HDAC3 (0.55) | HDAC1 | |
| SCHEMBL4844595 | 0.80 | MAPT (0.56) | HDAC1 | |
| Hydrochloric Acid SCHEMBL25337399 | 0.79 | CYP2D6 (0.44) | HDAC1 | |
| SCHEMBL28421388 | 0.78 | MAPT (0.59) | HDAC1 | |
| SCHEMBL28421444 | 0.78 | MAPT (0.59) | HDAC1 | |
| SCHEMBL28421401 | 0.78 | MAPT (0.59) | HDAC1 | |
| SCHEMBL28413601 | 0.78 | MAPT (0.59) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091594-B1 | AMINOCARBOXYLIC ACID DERIVATIVES | Sanraku Incorporated (JP) | 1986-01-22 | — | — | EP | disclosed |
| US-4528397-A | Aminocarboxylic acid derivatives | SANRAKU-OCEAN CO., LTD. (JP) | 1985-07-09 | — | — | US | disclosed |
| US-RE31617-E | ANTICOAGULANTS; HYPOTENSIVE AND BRONCHODILATOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1984-06-26 | — | — | US | disclosed |
| EP-0091594-A1 | Aminocarboxylic acid derivatives | Sanraku Incorporated (JP) | 1983-10-19 | — | — | EP | disclosed |
| US-3983120-A | HYPOTENSIVES, ANTICLOTTING | BRISTOL-MYERS COMPANY (US) | 1976-09-28 | — | — | US | disclosed |
| US-3932407-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTICOAGULANTS | BRISTOL-MYERS COMPANY (US) | 1976-01-13 | — | — | US | disclosed |