Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7434059 | 0.98 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4844595 | 0.94 | MAPT (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28415269 | 0.93 | MAPT (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28413601 | 0.93 | MAPT (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28421401 | 0.93 | MAPT (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL503569 | 0.93 | MAPT (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28417932 | 0.93 | MAPT (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28421388 | 0.93 | MAPT (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28421444 | 0.93 | MAPT (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL89295 | 0.88 | KEAP1 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 380 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020531-A1 | METHOD FOR SYNTHESIZING 5,8-DIAMINO-3,4-DIHYDRO-2H-1-NAPHTHALENONE AND INTERMEDIATE COMPOUND USED THEREIN | 江苏迈威康新药研发有限公司 | 2023-02-23 | — | — | WO | claimed |
| CN-115703712-A | Process for the synthesis of 5,8-diamino-3,4-dihydro-2H-1-naphthalenone and intermediate compounds useful therein | 江苏迈威康新药研发有限公司 | 2023-02-17 | — | — | CN | claimed |
| EP-3059004-B1 | METHOD FOR REMOVING SOX FROM GAS WITH COMPLEX ALCOHOL-AMINE SOLUTION | BEIJING BOYUAN HENGSHENG HIGH TECH CO LTD (CN) | 2021-06-30 | — | — | EP | claimed |
| CN-108276473-A | A kind of insect kassinin kinin analog and its application in control of insect | 中国农业大学 | 2018-07-13 | — | — | CN | claimed |
| US-9999852-B2 | Method for removing SOx from gas with compound alcohol-amine solution | BEIJING BOYUAN HENGSHENG HIGH-TECHNOLOGY CO., LTD (CN) | 2018-06-19 | — | — | US | claimed |
| CN-106456662-A | Compositions of pentosan polysulfate for oral administration and methods of use thereof | 奥利金制药公司 | 2017-02-22 | — | — | CN | claimed |
| US-20160243491-A1 | Method for Removing SOx from Gas with Compound Alcohol-Amine Solution | PEKING UNIVERSITY (CN) | 2016-08-25 | — | — | US | claimed |
| EP-3059004-A1 | METHOD FOR REMOVING SOX FROM GAS WITHNCOMPOUND ALCOHOL-AMINE SOLUTION | Beijing Boyuan-Hengsheng High-Technology Co., Ltd. (CN) | 2016-08-24 | — | — | EP | claimed |
| US-20090220604-A1 | AMINO ACIDS IN MICELLE PREPARATION | ANGIOTECH INTERNATIONAL AG (CH) | 2009-09-03 | — | — | US | claimed |
| US-7521216-B2 | Nitrilases and methods for making and using them | VERENIUM CORPORATION (US) | 2009-04-21 | — | — | US | claimed |
| US-20030032774-A1 | Novel opioid peptides for the treatment of pain | ASTRAZENECA AB | 2003-02-13 | — | — | US | claimed |
| US-5962710-A | Method of preparing salicyloylamino acids | EMISPHERE TECHNOLOGIES, INC. (US) | 1999-10-05 | — | — | US | claimed |
| EP-0883629-A1 | OLIGOPEPTIDES FOR DRUG DELIVERY | Emisphere Technologies, Inc. (US) | 1998-12-16 | — | — | EP | claimed |
| WO-1998050341-A1 | METHOD OF PREPARING SALICYLOYLAMINO ACIDS | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-11-12 | — | — | WO | claimed |
| CN-1039126-C | Tachiquinine antagonist tricyclic compounds, preparation of same and pharmaceutical compositions containing such compounds | MENARINI FARMA IND (IT) | 1998-07-15 | — | — | CN | claimed |
| CN-1183786-A | Bicyclic tachykinins antagonists, preparation thereof and their use in autagonistes composition | MENARINI FARMA IND (IT) | 1998-06-03 | — | — | CN | claimed |
| WO-1997031938-A9 | OLIGOPEPTIDES FOR DRUG DELIVERY | — | 1997-11-20 | — | — | WO | claimed |
| WO-1997031938-A1 | OLIGOPEPTIDES FOR DRUG DELIVERY | EMISPHERE TECHNOLOGIES, INC. (US) | 1997-09-04 | — | — | WO | claimed |
| US-5512548-A | CHOLESTERYL ESTER TRANSFER PROTEIN | SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH (US) | 1996-04-30 | — | — | US | claimed |
| CN-1080916-A | The quinic tricyclic compound of anti-column foot, its preparation method and contain the pharmaceutical composition of this compound | MENARINI FARMA IND (IT) | 1994-01-19 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032774-A1 | Novel opioid peptides for the treatment of pain | OPRL1, OPRK1, OPRM1 | HDAC3 2504/4885HDAC4 4086/4885HDAC1 4180/4885 |
| US-20090220604-A1 | AMINO ACIDS IN MICELLE PREPARATION | MLX, SLC1A5, BMX | HDAC3 4868/4885HDAC4 4803/4885HDAC1 4864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.