Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 13/20 | 0.58 |
| ▸ | ACE | P12821 | 12/20 | 0.58 |
| ▸ | CPA1 | P15085 | 11/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344465 | 0.88 | MME (0.59) | MMEACE2ACECPA1 | |
| SCHEMBL7411122 | 0.85 | ALDH1A1 (0.52) | MMEACE2ACECPA1 | |
| SCHEMBL7319115 | 0.82 | MME (0.50) | MMEACE | |
| SCHEMBL3638965 | 0.80 | MMEL1 (0.61) | MMEACE | |
| SCHEMBL7346747 | 0.80 | ALDH1A1 (0.43) | MMEACE2ACECPA1 | |
| SCHEMBL7361412 | 0.79 | CYP1A2 (0.47) | CPA1 | |
| SCHEMBL7361415 | 0.79 | CYP1A2 (0.47) | CPA1 | |
| SCHEMBL7311905 | 0.77 | MME (0.73) | MMEACE2ACECPA1 | |
| SCHEMBL7901163 | 0.76 | MME (0.78) | MMEACE2ACECPA1 | |
| SCHEMBL30091378 | 0.75 | MME (0.72) | MMEACE2ACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | claimed |
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |