Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | ADH5 | P11766 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308381 | 0.80 | JAK2 (0.50) | LMNAMAPTNOTUM | |
| SCHEMBL4672079 | 0.76 | ALDH1A3 (0.54) | TSHRNPC1RAB9APDE3BPDE3A | |
| SCHEMBL7313168 | 0.76 | TSHR (0.49) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL7317792 | 0.75 | ALDH1A3 (0.54) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1431759 | 0.75 | TNKS (0.47) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7311707 | 0.75 | KDR (0.48) | KMT2ARAB9A | |
| SCHEMBL2900371 | 0.75 | CCNE2 (0.47) | NPC1RAB9A | |
| SCHEMBL7306383 | 0.75 | MEN1 (0.48) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL2533488 | 0.74 | TSHR (0.84) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL12970128 | 0.73 | MKNK1 (0.40) | MKNK1MKNK2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596872-A | Imidazo[1,2-a]pyridines, and process for their preparation | SCHERING A.G. (DE) | 1986-06-24 | — | — | US | claimed |
| US-4596872-A | Imidazo[1,2-a]pyridines, and process for their preparation | SCHERING A.G. (DE) | 1986-06-24 | — | — | US | disclosed |