Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 7/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10374992 | 0.95 | PDE3B (0.39) | PDE3BPDE3AKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL10375053 | 0.92 | THRA (0.40) | PDE3BPDE3AKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL7320491 | 0.90 | L3MBTL1 (0.38) | PDE3BPDE3AKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL7320624 | 0.89 | L3MBTL1 (0.37) | PDE3BPDE3AKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL10376587 | 0.88 | L3MBTL1 (0.39) | KDM4EL3MBTL1SMN1; SMN2POLBCYP2D6 | |
| SCHEMBL10375748 | 0.88 | L3MBTL1 (0.41) | KDM4EL3MBTL1SMN1; SMN2POLBCYP2D6 | |
| SCHEMBL7307953 | 0.87 | PDE3B (0.42) | PDE3BPDE3AKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL10377014 | 0.85 | SMN1; SMN2 (0.39) | PDE3BPDE3AKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL10754694 | 0.84 | PDE3B (0.46) | PDE3BPDE3AKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL10374861 | 0.83 | L3MBTL1 (0.37) | PDE3BPDE3AKDM4EL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |