Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.39 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9427347 | 0.99 | MAOB (0.47) | MAOBSIGMAR1HTR1ACYP19A1METAP1 | |
| SCHEMBL7300027 | 0.94 | MAOB (0.51) | MAOBSIGMAR1HTR1ACYP19A1METAP1 | |
| SCHEMBL7309140 | 0.84 | CYP19A1 (0.42) | MAOBSIGMAR1HTR1ACYP19A1THRA | |
| Hydrochloric Acid SCHEMBL9426165 | 0.84 | CYP19A1 (0.41) | MAOBSIGMAR1HTR1ACYP19A1THRA | |
| SCHEMBL7315694 | 0.81 | MAOB (0.47) | MAOBSIGMAR1HTR1ACYP19A1CHRM2 | |
| SCHEMBL7303893 | 0.80 | CYP19A1 (0.49) | SIGMAR1HTR1ACYP19A1METAP1 | |
| Hydrochloric Acid SCHEMBL9425569 | 0.79 | CYP19A1 (0.48) | SIGMAR1HTR1ACYP19A1METAP1 | |
| SCHEMBL7304546 | 0.79 | ACHE (0.47) | SIGMAR1CYP19A1METAP1 | |
| Hydrochloric Acid SCHEMBL9426279 | 0.78 | METAP1 (0.47) | SIGMAR1HTR1ACYP19A1METAP1 | |
| SCHEMBL7303491 | 0.76 | CYP19A1 (0.50) | SIGMAR1HTR1ACYP19A1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581677-B1 | Cycloalkylalkylamines which are sigma-receptor ligands, process for preparing them and their application in therapy | JOUVEINAL INST RECH (FR) | 1997-01-08 | — | — | EP | disclosed |
| US-5326784-A | Psychological and gastrointestinal disorders | INSTITUT DE RECHERCHE JOUVEINAL (FR) | 1994-07-05 | — | — | US | disclosed |
| EP-0581677-A1 | Cycloalkylalkylamines which are sigma-receptor ligands, process for preparing them and their application in therapy | INSTITUT DE RECHERCHE JOUVEINAL (I.R.J) (FR) | 1994-02-02 | — | — | EP | disclosed |