Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6066298 | 1.00 | THRB (0.47) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL19775605 | 1.00 | THRB (0.47) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL21486242 | 1.00 | THRB (0.47) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL3242535 | 1.00 | THRB (0.47) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL3242533 | 1.00 | THRB (0.47) | THRBMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7304812 | 0.97 | THRB (0.45) | THRBMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7315214 | 0.97 | THRB (0.45) | THRBMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7304808 | 0.97 | THRB (0.45) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL3240402 | 0.97 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL3833315 | 0.97 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251542-A | Imino compounds | CIBA-GEIGY CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
| US-4153235-A | HYPOGLYCEMIC, HYPOTENSIVE, ANTIINFLAMMATORY, ANTICOAGULANT, DIURETIC ACTIVITIES | RICHARDSON-MERRELL INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4130652-A | 2-(Iminoethylidene)-pyrrolidines and tautomeric 2-(aminoethenyl)-1-pyrrolines | CIBA-GEIGY CORPORATION (US) | 1978-12-19 | — | — | US | disclosed |
| US-4126613-A | HYPOGLYCEMIC, HYPOTENSIVE, ANTIINFLAMMATORY, ANTICOAGULANT, DIURETIC | RICHARDSON-MERRELL INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4126621-A | HYPOGLYCEMIC, HYPOTENSIVE, ANTIINFLAMMATORY, ANTICOAGULANT, DIURETIC | RICHARDSON-MERRELL INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4126611-A | HYPOGLYCEMIC, HYPOTENSIVE, ANTIINFLAMMATORY, ANTICOAGULANT, DIURETIC | RICHARDSON-MERRELL INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4126612-A | HYPOGLYCEMIC, HYPOTENSIVE, ANTIINFLAMMATORY, ANTICOAGULANT, DIURETIC | Retter, Eugene O. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061746-A | Lactamimide inhibitors of gastrointestinal hypersecretion | RICHARDSON-MERRELL INC. (US) | 1977-12-06 | — | — | US | disclosed |