Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | UGCG | Q16739 | 2/20 | 0.42 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3164232 | 0.90 | TSHR (0.48) | TSHRKDM4EPOLBTACR1SLC1A1 | |
| SCHEMBL29337772 | 0.90 | TSHR (0.48) | TSHRKDM4EPOLBTACR1SLC1A1 | |
| SCHEMBL1569297 | 0.90 | TSHR (0.48) | TSHRKDM4EPOLBTACR1SLC1A1 | |
| Hydrochloric Acid SCHEMBL3347482 | 0.88 | TSHR (0.47) | TSHRKDM4EPOLBTACR1SLC1A1 | |
| SCHEMBL6120254 | 0.83 | TSHR (0.45) | TSHRTACR1SLC1A1TDP1L3MBTL1 | |
| SCHEMBL6120599 | 0.83 | TSHR (0.45) | TSHRTACR1SLC1A1TDP1L3MBTL1 | |
| SCHEMBL9636934 | 0.83 | TSHR (0.45) | TSHRTACR1SLC1A1TDP1L3MBTL1 | |
| SCHEMBL5339208 | 0.83 | TSHR (0.48) | TSHRKDM4EPOLBGBA1UGCG | |
| SCHEMBL17747743 | 0.83 | LTA4H (0.48) | TSHRSLC1A1HTTSMN1; SMN2MMP1 | |
| SCHEMBL17747744 | 0.83 | LTA4H (0.48) | TSHRSLC1A1HTTSMN1; SMN2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |