Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | RXRG | P48443 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300468 | 0.85 | RAB9A (0.44) | ITGB3ITGA2BMAOBMAOARAB9A | |
| SCHEMBL7307064 | 0.83 | ITGB3 (0.74) | ITGB3ITGA2BRAB9ANPC1ALDH1A1 | |
| SCHEMBL7349921 | 0.82 | ITGB3 (0.58) | ITGB3ITGA2BMAOBMAOARAB9A | |
| SCHEMBL7298184 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BRAB9AFAAHNPC1 | |
| SCHEMBL7298188 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BRAB9AFAAHNPC1 | |
| SCHEMBL4621845 | 0.81 | BACE1 (0.60) | ITGB3ITGA2BRAB9AFAAHNPC1 | |
| SCHEMBL7347857 | 0.78 | ITGB3 (0.64) | ITGB3ITGA2BPPARDFAAHCYP26A1 | |
| SCHEMBL7355172 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2BFAAHCYP26A1 | |
| SCHEMBL7297164 | 0.75 | CYP19A1 (0.51) | ITGB3ITGA2BMAPTCYP26A1MTNR1A | |
| SCHEMBL7303640 | 0.75 | ITGB3 (0.70) | ITGB3ITGA2BRAB9APPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |