Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 9/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.62 |
| ▸ | RELA | Q04206 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | F2RL3 | Q96RI0 | 8/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7320190 | 0.83 | ATP4A (0.61) | TP53MAPT | |
| SCHEMBL7312305 | 0.78 | TP53 (0.72) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10878341 | 0.75 | TP53 (1.00) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7312312 | 0.74 | FYN (0.43) | SMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL13186820 | 0.73 | TP53 (0.74) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3831821 | 0.72 | MEN1 (0.62) | TP53MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5309504 | 0.72 | SMN1; SMN2 (0.72) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7318618 | 0.72 | SMN1; SMN2 (0.65) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7320185 | 0.72 | TP53 (0.61) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7326102 | 0.71 | RARB (0.56) | TP53MAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880824-A | CARDIOVASCULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-14 | — | — | US | disclosed |