Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132717 | 0.99 | RARB (0.58) | RARBTP53TSHRPLA2G4BCA12 | |
| SCHEMBL6132844 | 0.92 | CA12 (0.53) | RARBTP53TSHRPLA2G4BCA12 | |
| SCHEMBL6539767 | 0.90 | MAPT (0.57) | RARBTP53TSHRPLA2G4BCA12 | |
| SCHEMBL7320722 | 0.88 | PTPN11 (0.51) | RARBTP53TSHRPLA2G4BCA12 | |
| Trifluoroacetic Acid SCHEMBL7316392 | 0.85 | TP53 (0.47) | RARBTP53CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL7323575 | 0.85 | CA12 (0.46) | RARBTP53CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL6538606 | 0.84 | TP53 (0.47) | RARBTP53CA12CA1CA2 | |
| SCHEMBL6132534 | 0.82 | TP53 (0.50) | RARBTP53CA12CA1CA2 | |
| SCHEMBL7318285 | 0.82 | CA12 (0.51) | TP53CA12CA1CA2CA9 | |
| SCHEMBL7321691 | 0.82 | CA12 (0.51) | TP53CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |