Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10431039 | 0.87 | DNMT1 (0.48) | ALDH1A1MAPTKDM4EDNMT1KDM4A | |
| SCHEMBL22290853 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EKDM4ACYP1A2 | |
| SCHEMBL10148012 | 0.81 | MEN1 (0.50) | ALDH1A1MAPTKDM4EKDM4AKMT2A | |
| SCHEMBL7318863 | 0.80 | DNMT1 (0.43) | ALDH1A1MAPTKDM4EDNMT1KDM4A | |
| SCHEMBL6773482 | 0.78 | KDM4A (0.54) | ALDH1A1MAPTKDM4EKDM4AKMT2A | |
| SCHEMBL7420624 | 0.78 | KDM4A (0.54) | ALDH1A1MAPTKDM4EKDM4AKMT2A | |
| SCHEMBL3096665 | 0.77 | ALDH1A1 (0.55) | ALDH1A1CYP1A2KMT2ATSHRMEN1 | |
| SCHEMBL1158293 | 0.76 | MAPT (0.71) | ALDH1A1MAPTKDM4EDNMT1KDM4A | |
| SCHEMBL1158294 | 0.76 | MAPT (0.71) | ALDH1A1MAPTKDM4EDNMT1KDM4A | |
| SCHEMBL8125444 | 0.75 | KDM4A (0.51) | ALDH1A1MAPTKDM4EKDM4AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4508645-A | CYCLIC OLIGOPEPTIDE CONTAINING PENICILLAMINE RESIDE | CESKOSLOVENSKA AKADEMIE VED (CS) | 1985-04-02 | — | — | US | disclosed |