Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419555 | 1.00 | GLO1 (1.00) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL29419558 | 1.00 | GLO1 (1.00) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL6137191 | 1.00 | GLO1 (1.00) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL29419556 | 1.00 | GLO1 (1.00) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL6137188 | 1.00 | GLO1 (1.00) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL8018753 | 0.95 | GLO1 (0.90) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL9401908 | 0.90 | GLO1 (0.82) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL9401912 | 0.90 | GLO1 (0.82) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL11776075 | 0.90 | GLO1 (0.82) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL11681247 | 0.90 | GLO1 (0.82) | GLO1KMT2ALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624024-A | Preparation method of high-purity nitrendipine | 乐声药业石家庄有限公司 | 2024-03-01 | — | — | CN | claimed |
| JP-62169793-A | — | — | None | — | — | JP | disclosed |
| CN-114149360-B | Preparation method of high-purity nitrendipine bulk drug | 天津太平洋化学制药有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117624024-A | Preparation method of high-purity nitrendipine | 乐声药业石家庄有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-116003311-A | Method for synthesizing nitrendipine by utilizing ionic liquid catalysis | 山东新华制药股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-111072553-B | Preparation method of nitrendipine | 北京鑫开元医药科技有限公司 | 2021-12-28 | — | — | CN | disclosed |
| CN-109734656-B | Preparation method of nitrendipine | 嘉实（湖南）医药科技有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-111072553-A | Preparation method of nitrendipine | 北京鑫开元医药科技有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-110551061-A | Preparation method of high-purity nitrendipine | SHANDONG XINHUA PHARMACEUTICAL | 2019-12-10 | — | — | CN | disclosed |
| US-6015906-A | Dimethylamine benzoate or p-anisate catalysed process for the preparation of 4-(nitrophenyl)-dihydropyridines | LUSOCHIMICA S.P.A. (IT) | 2000-01-18 | — | — | US | disclosed |
| US-3971791-A | VASODILATION, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |
| US-3959292-A | HYPOTENSIVE AGENTS, CORONARY DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |
| US-3951994-A | HYPOTENSIVE, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3951988-A | HYPOTENSIVE, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3948923-A | HYPOTENSIVE, VASODILATION | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | disclosed |
| US-3946026-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3939171-A | HYPOTENSIVE, VASODILATION | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | disclosed |
| US-3935220-A | VASODILATION, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-27 | — | — | US | disclosed |
| US-3935223-A | 2-Amino-1,4-dihydropyridine derivatives | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-27 | — | — | US | disclosed |
| US-3932645-A | CORONARY VASODILATORS, HYPOTENSIVE AGENTS | FARBENFABRIKEN BAYER AG (DT) | 1976-01-13 | — | — | US | disclosed |