Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 6/20 | 0.50 |
| ▸ | ADH1C | P00326 | 4/20 | 0.50 |
| ▸ | ADH1B | P00325 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18841464 | 0.97 | ADH1A (0.52) | ADH1AADH1CADH1BPHGDHFDPS | |
| SCHEMBL296264 | 0.97 | ADH1A (0.52) | ADH1AADH1CADH1BPHGDHFDPS | |
| SCHEMBL9551174 | 0.97 | ADH1A (0.52) | ADH1AADH1CADH1BPHGDHFDPS | |
| SCHEMBL15221572 | 0.94 | ADH1A (0.48) | ADH1AADH1CADH1BPHGDHFDPS | |
| SCHEMBL19754763 | 0.91 | ADH1A (0.44) | ADH1AADH1CADH1B | |
| SCHEMBL10036715 | 0.84 | ADH1B (0.39) | ADH1AADH1CADH1B | |
| SCHEMBL20438384 | 0.84 | ADH1B (0.39) | ADH1AADH1CADH1B | |
| SCHEMBL15996250 | 0.81 | ADH1A (0.45) | ADH1AADH1CADH1BPHGDHFDPS | |
| SCHEMBL14317675 | 0.78 | ADH1A (0.46) | ADH1AADH1CADH1BPHGDHFDPS | |
| SCHEMBL12250814 | 0.77 | ADH1A (0.56) | ADH1AADH1CADH1BPHGDHFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138335-B2 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20100029631-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-7601712-B2 | Such as (1)-2-(4-chloro-3-((2-chloro-4-(((2S)-4-methyl-3,4-dihydro-2H-1,4-benzoxazin-2-ly)methoxy)benzoyl)amino)phenyl)-2-methylpropanoic acid; prostaglandin receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| CN-1332161-A | Method for preparing sulfamine urea compound | AMERICAN CYANAMID CO (US) | 2002-01-23 | — | — | CN | disclosed |
| CN-1332160-A | Process for prep. of 4-hydroxy-phenyl butanone | AMERICAN CYANAMID CO (US) | 2002-01-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029631-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | GPR17, CYSLTR1, KIT | ADH1A 1663/4885ADH1C 1430/4885ADH1B 1976/4885 |
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | GPR17, CYSLTR1, KIT | ADH1A 1663/4885ADH1C 1430/4885ADH1B 1976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.