Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.68 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.68 |
| ▸ | PPARG | P37231 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684085 | 0.93 | AGTR1 (0.71) | AGTR1AGTR2PPARG | |
| SCHEMBL8566093 | 0.91 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL7309439 | 0.89 | PPARG (0.60) | AGTR1AGTR2PPARG | |
| SCHEMBL7310636 | 0.89 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL7306972 | 0.88 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL682612 | 0.88 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL7312953 | 0.87 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL13084055 | 0.86 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL683721 | 0.85 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8568722 | 0.85 | AGTR1 (0.61) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503785-A1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1992-09-16 | — | — | EP | disclosed |