Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568722 | 0.94 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL684085 | 0.93 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL7312663 | 0.91 | AGTR1 (0.68) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL8568424 | 0.89 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL8560448 | 0.89 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL7310636 | 0.89 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL7306972 | 0.88 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL682612 | 0.88 | AGTR1 (0.67) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL8559318 | 0.87 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8561502 | 0.86 | AGTR1 (0.55) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056140-C | Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease | SANKYO CO (JP) | 2000-09-06 | — | — | CN | claimed |
| EP-0603001-B1 | Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease | SANKYO CO (JP) | 1998-08-26 | — | — | EP | claimed |
| US-5459148-A | Cardiovascular disorders | SANKYO COMPANY, LIMITED (JP) | 1995-10-17 | — | — | US | claimed |
| CN-1095374-A | Biphenyl derivatives, their preparation and they are in the application for the treatment of hypertension and cardiac disease | SANKYO CO (JP) | 1994-11-23 | — | — | CN | claimed |
| EP-0603001-A1 | Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease | SANKYO COMPANY LIMITED (JP) | 1994-06-22 | — | — | EP | claimed |
| EP-0603001-B1 | Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease | SANKYO CO (JP) | 1998-08-26 | — | — | EP | disclosed |
| US-5459148-A | Cardiovascular disorders | SANKYO COMPANY, LIMITED (JP) | 1995-10-17 | — | — | US | disclosed |
| EP-0603001-A1 | Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease | SANKYO COMPANY LIMITED (JP) | 1994-06-22 | — | — | EP | disclosed |