Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303045 | 0.83 | NPSR1 (0.81) | KMT2ANPSR1HRH3MEN1F2 | |
| SCHEMBL13873309 | 0.83 | EPHX2 (0.77) | KMT2APOLBLMNAGAANPSR1 | |
| SCHEMBL5217325 | 0.82 | KDM4E (0.68) | KMT2ALMNANPSR1HRH3MEN1 | |
| SCHEMBL6559744 | 0.82 | KDM4E (0.68) | KMT2ALMNANPSR1HRH3MEN1 | |
| SCHEMBL5800630 | 0.81 | KDM4E (0.69) | KMT2ALMNANPSR1HRH3MEN1 | |
| SCHEMBL4197501 | 0.81 | KDM4E (0.69) | KMT2ALMNANPSR1HRH3MEN1 | |
| SCHEMBL28711147 | 0.81 | GAA (0.52) | KMT2APOLBLMNAGAAF2 | |
| SCHEMBL7298745 | 0.79 | HPGD (0.69) | KMT2ALMNAALDH1A1HPGDTSHR | |
| SCHEMBL13841219 | 0.78 | KMT2A (0.64) | KMT2APOLBGAANPSR1HRH3 | |
| SCHEMBL2422779 | 0.77 | LMNA (0.62) | KMT2APOLBLMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |