Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 6/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312690 | 1.00 | MEN1 (0.37) | MEN1KMT2ADPP4CSNK1ESLC6A2 | |
| SCHEMBL9168426 | 0.81 | ADORA3 (0.46) | DPP4SLC6A3DPP8 | |
| SCHEMBL9168915 | 0.81 | ADORA3 (0.46) | DPP4SLC6A3DPP8 | |
| SCHEMBL7304137 | 0.80 | ADORA3 (0.49) | — | |
| SCHEMBL7306807 | 0.80 | ADORA3 (0.49) | — | |
| SCHEMBL8880117 | 0.78 | F2 (0.39) | MEN1KMT2ADPP4CSNK1ESLC6A2 | |
| SCHEMBL8795598 | 0.73 | DPP4 (0.43) | MEN1KMT2ADPP4CSNK1EDPP8 | |
| SCHEMBL8795747 | 0.73 | DPP4 (0.43) | MEN1KMT2ADPP4CSNK1EDPP8 | |
| SCHEMBL495874 | 0.71 | CSNK1E (0.48) | MEN1KMT2ACSNK1ESLC6A4SLC6A3 | |
| SCHEMBL496353 | 0.70 | SPHK2 (0.45) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528242-A2 | Trifluoromethyl containing pseudopeptides | BAYER AG (DE) | 1993-02-24 | — | — | EP | disclosed |