Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15463143 | 0.78 | PDK2 (1.00) | PDK2 | |
| SCHEMBL28424202 | 0.77 | PDK2 (0.53) | PDK2 | |
| SCHEMBL18674882 | 0.76 | HTR2A (0.47) | PDK2 | |
| SCHEMBL27801451 | 0.75 | PDK2 (0.44) | PDK2 | |
| SCHEMBL18913699 | 0.73 | PDK2 (0.43) | PDK2 | |
| SCHEMBL23936830 | 0.72 | PDK2 (0.52) | PDK2 | |
| SCHEMBL30341830 | 0.72 | PDK2 (0.52) | PDK2 | |
| SCHEMBL2239449 | 0.72 | PDK2 (0.52) | PDK2 | |
| SCHEMBL24973268 | 0.71 | PDK2 (0.41) | PDK2 | |
| SCHEMBL12743231 | 0.71 | PDK2 (0.51) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395231-A1 | RECEPTOR INHIBITORS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) | 2021-12-23 | — | — | US | disclosed |
| US-7919825-B2 | Thin film transistors with poly(arylene ether) polymers as gate dielectrics and passivation layers | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395231-A1 | RECEPTOR INHIBITORS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND USE THEREOF | TACR1, TACR2, GPBAR1 | PDK2 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.