Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2695270 | 0.81 | BRD4 (0.46) | BRD4SPHK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2695273 | 0.81 | BRD4 (0.46) | BRD4SPHK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1833587 | 0.81 | BRD4 (0.47) | BRD4SPHK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL1833586 | 0.81 | BRD4 (0.47) | BRD4SPHK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL1759684 | 0.80 | BRD4 (0.47) | BRD4NPC1RAB9A | |
| SCHEMBL1759685 | 0.80 | BRD4 (0.47) | BRD4NPC1RAB9A | |
| SCHEMBL6486930 | 0.80 | BRD4 (0.46) | BRD4SPHK1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6486940 | 0.80 | BRD4 (0.46) | BRD4SPHK1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL18959547 | 0.79 | BRD4 (0.47) | BRD4SPHK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17020103 | 0.79 | SMN1; SMN2 (0.41) | BRD4SPHK1PPARGPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |