Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | STS | P08842 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17010140 | 0.84 | CTSK (0.41) | CTSKKMT2AMEN1POLBCRBN | |
| SCHEMBL1833587 | 0.80 | BRD4 (0.47) | BRD4SPHK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL1833586 | 0.80 | BRD4 (0.47) | BRD4SPHK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7312969 | 0.79 | BRD4 (0.45) | BRD4SPHK1KMT2AMEN1POLB | |
| SCHEMBL6486930 | 0.79 | BRD4 (0.46) | BRD4SPHK1KMT2AMEN1HSD11B2 | |
| SCHEMBL6486940 | 0.79 | BRD4 (0.46) | BRD4SPHK1KMT2AMEN1HSD11B2 | |
| SCHEMBL4435099 | 0.79 | BRD4 (0.50) | BRD4SPHK1KMT2AMEN1HSD11B2 | |
| SCHEMBL1830635 | 0.79 | SPHK1 (0.39) | BRD4SPHK1KMT2AMEN1HSD11B2 | |
| SCHEMBL1830631 | 0.79 | SPHK1 (0.39) | BRD4SPHK1KMT2AMEN1HSD11B2 | |
| SCHEMBL18963700 | 0.79 | SPHK1 (0.47) | BRD4SPHK1CTSKCRBNHSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10294233-B2 | Treatment of H. pylori infections using MTAN inhibitors | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2019-05-21 | — | — | US | disclosed |
| US-20190016730-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2019-01-17 | — | — | US | disclosed |
| US-20170166571-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2017-06-15 | — | — | US | disclosed |
| US-20170166571-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166571-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | MTAP, PNP, UNG | BRD4 3050/4885SPHK1 3541/4885CTSK 830/4885 |
| US-10294233-B2 | Treatment of H. pylori infections using MTAN inhibitors | MTAP, PNP, UNG | BRD4 3050/4885SPHK1 3541/4885CTSK 830/4885 |
| US-20190016730-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | MTAP, PNP, UNG | BRD4 3050/4885SPHK1 3541/4885CTSK 830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.