Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | TLR4 | O00206 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | FBP1 | P09467 | 5/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 2/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798355 | 0.85 | RXRA (0.58) | RXRATLR4TLR2FBP1PRMT1 | |
| SCHEMBL798354 | 0.85 | RXRA (0.58) | RXRATLR4TLR2FBP1PRMT1 | |
| SCHEMBL497 | 0.80 | FBP1 (0.54) | RXRATLR4TLR2FBP1PRMT1 | |
| SCHEMBL496 | 0.80 | FBP1 (0.54) | RXRATLR4TLR2FBP1PRMT1 | |
| SCHEMBL27673733 | 0.79 | FBP1 (0.55) | RXRATLR4TLR2FBP1PRMT1 | |
| SCHEMBL28594822 | 0.79 | RXRA (0.54) | RXRATLR4TLR2FBP1PRMT1 | |
| SCHEMBL28204740 | 0.77 | RXRA (0.76) | RXRATLR4TLR2FBP1PRMT1 | |
| SCHEMBL27947394 | 0.77 | RXRA (0.76) | RXRATLR4TLR2FBP1PRMT1 | |
| SCHEMBL9357677 | 0.74 | RXRA (0.53) | RXRATLR4TLR2FBP1PRMT1 | |
| SCHEMBL8613856 | 0.74 | TSHR (0.41) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |