Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309568 | 0.90 | PDE3B (0.47) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL10376732 | 0.88 | PDE3B (0.44) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL7312404 | 0.84 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL7317629 | 0.83 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL10375666 | 0.82 | PDE3B (0.47) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL10374565 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL11013555 | 0.79 | BACE1 (0.46) | ALDH1A1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL7318422 | 0.79 | BACE1 (0.46) | ALDH1A1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL10374567 | 0.78 | MEN1 (0.41) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL7306561 | 0.78 | BACE1 (0.45) | ALDH1A1SMN1; SMN2MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |