Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318784 | 0.90 | PDE3B (0.47) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7313259 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7317629 | 0.84 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7315992 | 0.74 | PDE3B (0.49) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7309568 | 0.74 | PDE3B (0.47) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7311180 | 0.74 | PDE3B (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL10377117 | 0.74 | PDE3B (0.42) | ALDH1A1MAPTSMN1; SMN2MAPK1KMT2A | |
| SCHEMBL10375666 | 0.73 | PDE3B (0.47) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10376732 | 0.73 | PDE3B (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL7318725 | 0.72 | LMNA (0.54) | ALDH1A1SMN1; SMN2NPC1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |