Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.37 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307231 | 0.89 | CYP2C19 (0.38) | LMNAKCNN4ALDH1A1 | |
| SCHEMBL12340194 | 0.76 | LMNA (0.43) | LMNACA12CA7CA9CA14 | |
| SCHEMBL1080987 | 0.76 | CYP2D6 (0.37) | KCNN4ALDH1A1 | |
| SCHEMBL10387238 | 0.76 | CNR1 (0.55) | LMNACNR1CNR2PTPRCKCNN4 | |
| SCHEMBL19454902 | 0.75 | CNR1 (0.54) | LMNACNR1CNR2PTPRCPTPN13 | |
| SCHEMBL7311082 | 0.74 | AKT1 (0.36) | LMNACA12CA7CA9CA14 | |
| SCHEMBL7311089 | 0.74 | AKT1 (0.36) | LMNACA12CA7CA9CA14 | |
| SCHEMBL7307298 | 0.73 | CYP1A2 (0.33) | LMNAKCNN4 | |
| SCHEMBL7318358 | 0.73 | FFAR4 (0.38) | TBXAS1 | |
| SCHEMBL14002768 | 0.72 | CYP2C19 (0.53) | LMNACNR1CNR2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |