Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313272 | 0.89 | LMNA (0.42) | ALDH1A1KCNN4LMNA | |
| SCHEMBL7318358 | 0.82 | FFAR4 (0.38) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL7308333 | 0.78 | ADRA1A (0.40) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL1080987 | 0.78 | CYP2D6 (0.37) | CYP2C19HIF1AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7313602 | 0.76 | KCNH2 (0.37) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL7313549 | 0.76 | PTGER4 (0.39) | CYP2C19HIF1AMAPTRXFP1ALDH1A1 | |
| SCHEMBL7307298 | 0.75 | CYP1A2 (0.33) | CYP2C19HIF1AMAPTCYP1A2CYP2D6 | |
| SCHEMBL7314042 | 0.75 | CACNA1G (0.46) | KCNN4 | |
| SCHEMBL7311082 | 0.74 | AKT1 (0.36) | CYP2C19HIF1AMAPTALDH1A1CYP1A2 | |
| SCHEMBL7311089 | 0.74 | AKT1 (0.36) | CYP2C19HIF1AMAPTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |