⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20897852 | 0.97 | — | — | |
| SCHEMBL1457345 | 0.77 | TRPA1 (0.42) | — | |
| SCHEMBL19348074 | 0.77 | TRPA1 (0.42) | — | |
| SCHEMBL458309 | 0.74 | — | — | |
| SCHEMBL950500 | 0.74 | — | — | |
| SCHEMBL467841 | 0.74 | — | — | |
| SCHEMBL392205 | 0.74 | — | — | |
| SCHEMBL1445277 | 0.72 | — | — | |
| SCHEMBL996978 | 0.72 | — | — | |
| SCHEMBL37426 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054478-A | PREVENTION OR CURE OF FUNGAL DISEASES IN HUMANS AND ANIMALS;PREPARED BY BIIOTRANSFORMATION | GLAXO WELLCOME S.A. (ES) | 2000-04-25 | — | — | US | disclosed |
| US-5952334-A | SORDARIN DERIVATIVES; FUNGICIDES | GLAXO WELLCOME S.A. (ES) | 1999-09-14 | — | — | US | disclosed |
| EP-0753001-B1 | ANTIFUNGAL SORDARIDIN DERIVATIVES | GLAXO WELLCOME SA (ES) | 1999-09-08 | — | — | EP | disclosed |
| EP-0791007-B1 | ANTIFUNGAL SORDARIDIN DERIVATIVES | GLAXO WELLCOME SA (ES) | 1999-08-11 | — | — | EP | disclosed |
| US-5854280-A | Antifungal sordaridin derivatives | GLAXO WELLCOME S.A. (ES) | 1998-12-29 | — | — | US | disclosed |
| EP-0753001-A1 | ANTIFUNGAL SORDARIDIN DERIVATIVES | Glaxo Wellcome S.A. (ES) | 1997-01-15 | — | — | EP | disclosed |
| EP-0712859-A1 | Antifungal Sordarin derivatives | GLAXO, S.A. (ES) | 1996-05-22 | — | — | EP | disclosed |
| WO-1996014326-A1 | ANTIFUNGAL SORDARIDIN DERIVATIVES | GLAXO WELLCOME S.A. (ES) | 1996-05-17 | — | — | WO | disclosed |
| EP-0711784-A1 | Antifungal Sordarin derivatives | GLAXO, S.A. (ES) | 1996-05-15 | — | — | EP | disclosed |
| EP-0711783-A1 | Antifungal Sordarin derivatives | GLAXO, S.A. (ES) | 1996-05-15 | — | — | EP | disclosed |