SCHEMBL458309

SCHEMBL458309

C=CCSC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL950500 1.00
SCHEMBL19348074 0.79 TRPA1 (0.42)
SCHEMBL1457345 0.79 TRPA1 (0.42)
SCHEMBL467841 0.77
SCHEMBL9740049 0.76
SCHEMBL10817181 0.76 MITF (0.33)
SCHEMBL5807176 0.74
SCHEMBL1445277 0.74
SCHEMBL7313571 0.74
SCHEMBL28086 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181153-A Preparation method of 1- [ (2-propenyl sulfenyl) formyl ] -4- (2-methylphenyl) -5-amino-1H-pyrazol-3-ketone 山东广浦生物科技有限公司 2022-03-15 CN claimed
CN-109415297-A New antibiotic 布洛斯 & 库珀制药私人有限公司 2019-03-01 CN claimed
CN-107922288-A SYNTHESIS OF ARYL COMPOUNDS 布洛斯 & 库珀制药私人有限公司 2018-04-17 CN claimed
CN-104588113-B Macromolecule load catalyst and its application in arenes selectivity chlorination reaction 东南大学 2017-08-04 CN claimed
US-9127107-B2 Aqueous amphiphilic copolymer emulsions having controlled viscosity and methods for making the same ROHM AND HAAS COMPANY (US) 2015-09-08 US claimed
CN-104588113-A Polymer supported catalyst and application thereof in aromatic selective chlorination reaction UNIV SOUTHEAST 2015-05-06 CN claimed
CN-103623867-A Composite catalyst for selective chlorination of aromatic compounds and application thereof UNIV SOUTHEAST 2014-03-12 CN claimed
EP-2018162-A2 METHODS FOR THE DELIVERY OF A BETA2 AGONIST TO INDUCE BRONCHODILATION AND FORMULATIONS FOR USE IN THE SAME Tika Läkemedel AB (SE) 2009-01-28 EP claimed
EP-1973550-A2 METHODS AND SYSTEMS FOR THE DELIVERY OF CORTICOSTEROIDS HAVING AN ENHANCED PHARMACOKINETIC PROFILE Tika Läkemedel AB (SE) 2008-10-01 EP claimed
EP-1971348-A2 SYSTEMS AND METHODS FOR THE DELIVERY OF CORTICOSTEROIDS HAVING AN INCREASED LUNG DEPOSITION Tika Läkemedel AB (SE) 2008-09-24 EP claimed
WO-2007075801-A2 METHOD AND SYSTEM FOR THE DELIVERY OF CORTICOSTEROIDS HAVING AN ENHANCED PHARMACOKINETIC PROFILE TIKA LÄKEMEDEL AB (SE) 2007-07-05 WO claimed
WO-2007075859-A2 SYSTEMS AND METHODS FOR THE DELIVERY OF CORTICOSTEROIDS HAVING AN INCREASED LUNG DEPOSITION TIKA LÄKEMEDEL AB (SE) 2007-07-05 WO claimed
CN-1193622-A Method for production of sulfide group-containing thiol compound NIPPON CATALYTIC CHEM IND (JP) 1998-09-23 CN claimed
US-5290519-A Cardiovascular disorders DIAGNOSTIC MARKERS, INC. (US) 1994-03-01 US claimed
US-5227307-A Binding metals to thiol groups of tissue proteins DIAGNOSTIC MARKERS, INC. (US) 1993-07-13 US claimed
EP-0334427-B1 ALKYL SULPHONYL PEROXYCARBOXYLIC ACIDS AND BLEACHING AND DETERGENT COMPOSITIONS CONTAINING THE SAME AKZO N.V. (NL) 1992-06-10 EP claimed
EP-0334427-A1 Alkyl sulphonyl peroxycarboxylic acids and bleaching and detergent compositions containing the same AKZO N.V. (NL) 1989-09-27 EP claimed
US-4185155-A Production of alkyl (alkylthio) carboxylates POLAROID CORPORATION (US) 1980-01-22 US claimed
US-4168278-A DECYCLIZATION, AMIDATION THE DOW CHEMICAL COMPANY (US) 1979-09-18 US claimed
US-3951664-A Light-sensitive material having developers embedded therein AGFA-GEVAERT, A.G. (DT) 1976-04-20 US claimed