Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 3/20 | 0.52 |
| ▸ | FNTB | P49356 | 3/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764116 | 0.92 | CYP2D6 (0.59) | CTSCFNTAFNTBPGGT1BCYP2D6 | |
| Hydrochloric Acid SCHEMBL11094924 | 0.91 | CYP2D6 (0.58) | CTSCFNTAFNTBPGGT1BCYP2D6 | |
| SCHEMBL9366600 | 0.86 | ANPEP (0.59) | CTSCFNTAFNTBPGGT1BKMT2A | |
| SCHEMBL6819534 | 0.86 | ANPEP (0.59) | CTSCFNTAFNTBPGGT1BKMT2A | |
| SCHEMBL14444028 | 0.85 | POLB (0.55) | CA1POLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8686936 | 0.84 | ANPEP (0.57) | CTSCFNTAFNTBPGGT1BKMT2A | |
| SCHEMBL20366256 | 0.84 | MMP2 (0.55) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL7305453 | 0.83 | CNR1 (0.57) | CTSCFNTAFNTBPGGT1B | |
| SCHEMBL8936109 | 0.82 | CA1 (0.57) | CA1FNTAFNTBPGGT1BPOLB | |
| SCHEMBL8615413 | 0.82 | DPP7 (0.60) | POLBCYP2D6CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |