SCHEMBL7313656

SCHEMBL7313656

NC(=O)C(CCCCCOc1c(Cl)ccc2c1N=C1NC(=O)C(CO)N1C2)N1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 10/20 0.40
PDE3A Q14432 10/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7313658 0.83 PDE3B (0.43) PDE3BPDE3A
SCHEMBL7316653 0.81 PDE3B (0.40) PDE3BPDE3A
SCHEMBL7320349 0.78 PDE3B (0.37) PDE3BPDE3A
SCHEMBL7312180 0.76 PDE3B (0.59) PDE3BPDE3A
SCHEMBL7309032 0.75 PDE3B (0.58) PDE3BPDE3A
SCHEMBL7317488 0.74 PDE3B (0.47) PDE3BPDE3A
SCHEMBL7310186 0.72 PDE3B (0.47) PDE3BPDE3A
SCHEMBL7310194 0.71 PDE3B (0.47) PDE3BPDE3A
SCHEMBL7320601 0.71 PDE3B (0.35) PDE3BPDE3A
SCHEMBL7305725 0.68 PDE3B (0.65) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed