Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320610 | 0.85 | PDE3B (0.34) | PDE3BPDE3ALMNATSHRCYP1A2 | |
| SCHEMBL7320606 | 0.81 | PDE3B (0.37) | PDE3BPDE3ALMNATSHRCYP1A2 | |
| SCHEMBL7316989 | 0.80 | MAPT (0.32) | PDE3BPDE3ALMNAHPGDMAPT | |
| SCHEMBL7319827 | 0.79 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL7315285 | 0.76 | PDE3B (0.41) | PDE3BPDE3ALMNATSHRMAPT | |
| SCHEMBL7308814 | 0.75 | PDE3B (0.52) | PDE3BPDE3A | |
| SCHEMBL7313656 | 0.71 | PDE3B (0.40) | PDE3BPDE3A | |
| SCHEMBL7319841 | 0.71 | PDE3B (0.48) | PDE3BPDE3A | |
| SCHEMBL7312638 | 0.69 | MAPT (0.35) | LMNACYP3A4HPGDMAPTNPSR1 | |
| SCHEMBL7316945 | 0.68 | ALDH1A1 (0.36) | LMNACYP1A2CYP3A4CYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |