Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432705 | 0.80 | CA12 (0.46) | CA12CA7CA14L3MBTL1SMN1; SMN2 | |
| SCHEMBL11070402 | 0.77 | SMN1; SMN2 (0.39) | CA12CA7CA14L3MBTL1SMN1; SMN2 | |
| SCHEMBL13968028 | 0.74 | CA12 (0.54) | CA12CA7CA14L3MBTL1SMN1; SMN2 | |
| SCHEMBL28084234 | 0.71 | LMNA (0.55) | SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL21423124 | 0.70 | CA12 (0.54) | CA12CA7CA14L3MBTL1SMN1; SMN2 | |
| SCHEMBL465093 | 0.69 | CA12 (0.48) | CA12CA7CA14L3MBTL1SMN1; SMN2 | |
| SCHEMBL13943186 | 0.69 | CA12 (0.48) | CA12CA7CA14L3MBTL1SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL28632199 | 0.68 | SMN1; SMN2 (0.42) | CA12CA7CA14L3MBTL1SMN1; SMN2 | |
| SCHEMBL27896468 | 0.68 | CA12 (0.46) | CA12CA7CA14L3MBTL1SMN1; SMN2 | |
| Water SCHEMBL27714980 | 0.68 | CA12 (0.46) | CA12CA7CA14L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376655-A | Elastase inhibitor | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| US-5247084-A | Inhibitors of elastase | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| US-5077428-A | Antiinflammatory agents | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-4975464-A | ADMINISTERING DERIVATIVES OF P-GUANIDINOBENZOIC ACID | IMAKI KATSUHIRO (JP) | 1990-12-04 | — | — | US | disclosed |
| US-4843094-A | ELASTASE INHIBITOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |