Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL27818909 | 0.80 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL28051043 | 0.80 | CA12 (0.44) | SMN1; SMN2CA12CA7CA14TSHR | |
| SCHEMBL3634165 | 0.80 | CA12 (0.44) | SMN1; SMN2CA12CA7CA14TSHR | |
| Acetamide SCHEMBL6559564 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2CA12CA7CA14TSHR | |
| Sulfuric Acid SCHEMBL21616458 | 0.80 | CA12 (0.52) | SMN1; SMN2CA12CA7CA14TSHR | |
| Sulfuric Acid SCHEMBL28051044 | 0.80 | CA12 (0.52) | SMN1; SMN2CA12CA7CA14TSHR | |
| SCHEMBL3806089 | 0.78 | CA12 (0.50) | SMN1; SMN2CA12CA7CA14TSHR | |
| Fluoride SCHEMBL3439210 | 0.77 | — | — | |
| SCHEMBL7313667 | 0.77 | CA12 (0.46) | SMN1; SMN2CA12CA7CA14TSHR | |
| Sulfamate SCHEMBL27744770 | 0.76 | CA7 (0.48) | SMN1; SMN2CA12CA7CA14TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444682-A | OF HYDROXY AMINO ACIDS OR PEPTIDES CONTAINING SAME | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1984-04-24 | — | — | US | disclosed |